---
title: "Prof. Nicolai Cramer Vortrag Efficiency in Catalyst Design for Asymmetric Catalysis im Raum A12.232, TU Chemnitz; Berechnungsbasierte Vorhersagen verbessern Katalysatorenauswahl"
sdDatePublished: "2026-08-11T15:35:00Z"
source: "https://www.tu-chemnitz.de/chemie/GDCh/files/20261022.pdf"
topics:
  - name: "chemistry"
    identifier: "medtop:20000725"
  - name: "scientific research"
    identifier: "medtop:20000735"
  - name: "university"
    identifier: "medtop:20000407"
locations:
  - "Lausanne"
---


Prof. Nicolai Cramer Vortrag Efficiency in Catalyst Design for Asymmetric Catalysis im Raum A12.232, TU Chemnitz; Berechnungsbasierte Vorhersagen verbessern Katalysatorenauswahl

Folie 1

Fakultät für Naturwissenschaften
Institut für Chemie
Vortrag
von Herrn
Prof. Nicolai
Cramer
EPFL, SB, Institute of Chemistry
and Chemical Engineering,
Laboratory of Asymmetric
Catalysis and Synthesis
Lausanne, Switzerland
lädt ein
gemeinsam mit der Gesellschaft
Deutscher Chemiker
zum
am:
22.10.2026
um:
17:00 Uhr
wo:
im Raum A12.232
Gäste sind herzlich willkommen!
Prof. Dr. Michael Sommer
Telefon: 0371 / 531 32507
E-Mail: michael.sommer@chemie.tu-chemnitz.de
“Efficiency in
Catalyst Design for
Asymmetric
Catalysisi:
Rationality,
Diversity,
Preditability…Luck”

Fakultät für Naturwissenschaften
Institut für Chemie
Prof. Dr. Michael Sommer
Telefon: 0371 / 531 32507
E-Mail: michael.sommer@chemie.tu-chemnitz.de
Prof. Nicolai Cramer
EPFL, SB, Institute of Chemistry
and Chemical Engineering,
Laboratory of Asymmetric Catalysis
and Synthesis
Lausanne, Switzerland
EFFICIENCY IN CATALYST DESIGN FOR ASYMMETRIC CATALYSISI:
RATIONALITY, DIVERSITY, PREDICTABILITY…LUCK?
Access to robust tailored chiral ligands is of critical importance for advances in homogenous
enantioselective catalysis. The design and development of novel ligand libraries is often a
time-consuming and often tedious trial-and-error process. We seek to identify new privileged
chiral elements / scaffolds which could be rapidly adapted and used for a broad range of
reaction types. Pairing the structural data of the chiral micro environments of the catalytically
active sites with computational selectivity predictions sharpens the focus on the preparation
of “high potential” catalyst candidates for the library. The presentation will cover recent
examples of my laboratory.[1-4]
Figure 1. Streamlined access to Cpx-metal catalysts
References:
[1] B. Van Den Bossche, N. Cramer, J. Am. Chem. Soc. 2026, 148, 3775-3787.
[2] Y.-X. Cao, A.-S. Chauvin, S. Tong, L. Alama, N. Cramer, Nat. Catal. 2025, doi: 10.1038 /s41929-025-01352-3.
[3] L. K. Verdhi, M. D. Wodrich, N. Cramer, J. Am. Chem. Soc. 2025, 147, 15041.
[4] Y. S. Ye, A. Laverny, M. D. Wodrich, R. Laplaza, F. Fadaei-Tirani, R. Scopelliti, C. Corminboeuf, N. Cramer, J. Am. Chem. Soc.
2024, 146, 34786.