Forschungszentrum Borstel, Experimentelle Mykologie und Mikrobiomforschung, Leibniz Lungenzentrum; pH adaptation switch in fungi, therapeutic implications for diagnostics
Experimentelle Mykologie und Mikrobiomforschung – Forschungszentrum Borstel, Leibniz Lungenzentrum
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Pulmonary fungal infections are a major and growing threat to human health. Our goal is to uncover the evolutionary and molecular mechanisms that enable fungal pathogens to cause disease and resist treatment. By leveraging genomics, microbiome science, and experimental biology, we aim to advance new strategies for diagnosis, prevention, and therapy.
“Flipping the switch on fungal pH adaptation”. Wellcome Trust. 2026-2031
CIFAR Azrieli Global Scholar Program. 2025-2027
“Environmental interactions shape human virulence in fungi”. Boeringer Ingelheim Foundation. 2025-2027
“Fungal RNA Transmission Impacting Human Epigenome Regulation”. Leibniz Collaborative Excellence. 2024-2027
EUCAST antifungal susceptibility testing of moulds and yeasts
Genetic manipulation of filamentous fungi (e.g. Aspergillus fumigatus)
Isolation of genomic DNA and RNA from fungi and host tissues, including high molecular weight DNA
Spectophotometric and fluorometric quality control of DNA and RNA
Illumina, PacBio, and Oxford Nanopore sequencing
Eukaryotic genome assembly and annotation
Amplicon-based profiling of bacterial and fungal communities (e.g. 16S and ITS amplicons)
Metagenome assembly, binning, annotation, and taxonomic profiling
Transcriptome analysis, including dual (host-pathogen) RNAseq
Geneset enrichment and pathway analysis
Additional publications of Amelia Barber not affiliated with the Research Center Borstel barber-lab.com
Additional publications of Amelia Barber not affiliated with the Research Center Borstel
Prof. Dr. Amelia E. Barber
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