---
title: "Forschungszentrum Borstel, Experimentelle Mykologie und Mikrobiomforschung, Leibniz Lungenzentrum; pH adaptation switch in fungi, therapeutic implications for diagnostics"
sdDatePublished: "2026-08-20T12:24:00Z"
source: "https://fz-borstel.de/de/forschung-am-fzb/chronische-lungenerkrankungen/experimentelle-mykologie-und-mikrobiomforschung"
topics:
  - name: "medical research"
    identifier: "medtop:20000737"
  - name: "genetics"
    identifier: "medtop:20000721"
  - name: "biotechnology"
    identifier: "medtop:20000711"
locations:
  - "Borstel"
  - "Germany"
---


Forschungszentrum Borstel, Experimentelle Mykologie und Mikrobiomforschung, Leibniz Lungenzentrum; pH adaptation switch in fungi, therapeutic implications for diagnostics

Experimentelle ­Mykologie und ­Mikrobiomforschung – Forschungszentrum Borstel, Leibniz Lungenzentrum

Additional information and news from the group can be found on its external website:

Pulmonary fungal infections are a major and growing threat to human health. Our goal is to uncover the evolutionary and molecular mechanisms that enable fungal pathogens to cause disease and resist treatment. By leveraging genomics, microbiome science, and experimental biology, we aim to advance new strategies for diagnosis, prevention, and therapy.

"Flipping the switch on fungal pH adaptation". Wellcome Trust. 2026-2031

CIFAR Azrieli Global Scholar Program. 2025-2027

"Environmental interactions shape human virulence in fungi”. Boeringer Ingelheim Foundation. 2025-2027

"Fungal RNA Transmission Impacting Human Epigenome Regulation”. Leibniz Collaborative Excellence. 2024-2027

EUCAST antifungal susceptibility testing of moulds and yeasts

Genetic manipulation of filamentous fungi (e.g. Aspergillus fumigatus)

Isolation of genomic DNA and RNA from fungi and host tissues, including high molecular weight DNA

Spectophotometric and fluorometric quality control of DNA and RNA

Illumina, PacBio, and Oxford Nanopore sequencing

Eukaryotic genome assembly and annotation

Amplicon-based profiling of bacterial and fungal communities (e.g. 16S and ITS amplicons)

Metagenome assembly, binning, annotation, and taxonomic profiling

Transcriptome analysis, including dual (host-pathogen) RNAseq

Geneset enrichment and pathway analysis

Additional publications of Amelia Barber not affiliated with the Research Center Borstel barber-lab.com

Additional publications of Amelia Barber not affiliated with the Research Center Borstel

Prof. Dr. Amelia E. Barber

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