Our group investigates eosinophils in the gastrointestinal tract; to uncover pleiotropic roles in health and disease
Our group investigates eosinophils in the gastrointestinal tract; to uncover pleiotropic roles in health and disease Master Thesis Topics Biomedicine (Alphabetically sorted by supervisor name) Mucosal immunology of the gastrointestinal tract Short description Our group is interested in understanding how eosinophils, a highly abundant cellular subset residing in the gastrointestinal tract – control the balance between intestinal homeostasis and inflammation and contribute to the development of colorectal cancer. We are using a combination of experimental disease models, patient cohorts, sequencing, flow-cytometry and microscopy techniques - together with new tools specifically targeting the eosinophil lineage - to investigate the mechanisms driving the pleiotropic activities of these cells in intestinal health and disease. Keywords Eosinophils, mucosal immunology, inflammatory bowel diseases, colorectal cancer, microbiota Supervisor Institute E-mail Phone Prof. Isabelle Arnold Institute of Experimental Immunology, Mucosal Immunology Group arnold@immunology.uzh.ch 0446353730 Conditions Candidates are expected to show strong commitment and motivation, and to have a solid understanding of basic immunology. Candidates should further be ready to work with mice. Links https://www.immunology.uzh.ch/en/researchunit/mucosalimmunology/ research.html ...